A Case of Malaria Complicated with Erythematous Rash

Patient, A. A., aged 24 years, was admitted in the emergency ward of the Medical College Hospital on the 5th April, 1936, with a history of high quotidian fever for 5 days. The immediate cause of his seeking admission was the appearance of a peculiar erythematous rash all over his body without any sensation of itching. This rash appeared on the fourth day of the fever; his eyes were congested and tonsils were inflamed. His liver and spleen were not palpable and no abnormality was detected in his heart and lungs. On examination of his blood, malignant and benign tertian malarial parasites were found in considerable numbers. Ten grains of quinine bihydrochloride was injected intramuscularly on the same day and the temperature began to fall slowly and steadily. The rash disappeared totally within 14 hours after the injection of quinine. The fever was brought under control by subsequent oral administration of quinine (8 grs., thrice daily). The temperature became normal from the 9th April. The patient was discharged with advice to continue quinine and plasmochin.